There are over 80 studies on hops and health. Below is a quick synopsis of the study highlights that you can look up online. The more comprehensive studies are called “Reviews” because they take a look at a number of studies and capsulize the ideas. 

The great news is that hops is now bioavailable under a proprietary and patented process offered only in Hops 4 Health. 

 *Not all of the studies below directly relate to HOPS 4 resins but do show how comprehensively this one product has been studied. These statements and studies have not been evaluated by the Food and Drug Administration. HOPS 4 Health is not intended to diagnose, treat, cure or prevent any disease. Studies mentioned are for your research and reference not to state that HOPS 4 Health will accomplish similar results.  

Brain and Memory Studies

Tatsuhiro Ayabe, et al, A Review Improving Effects of Hop-Derived Bitter Acids in Beer on Cognitive Functions: A New Strategy for Vagus Nerve Stimulation Biomolecules Published: 13 January 2020 Click here to view!

They determined that Hops bitters: (like Hops 4 Health)

  • Enhanced hippocampus-dependent memory and prefrontal cortex-associated cognitive function
  • Enhance memory functions
  • Enhance cognitive function via Vagus nerve stimulation.
  • It is safe
  • Hops can stop neuroinflammation and cognitive impairments
  • Prevent obesity induced cognitive decline

These effects can be stopped by interrupting the Vagus nerve signals, which indicates that the Vagus nerve is critical for making the effects happen. It is a gut to brain connection not dependent on the blood brain barrier.

Lowering Blood Sugar and A1c Levels Produces Weight Loss

Methods – Ninety-four subjects with prediabetes were randomly divided into four groups. A 12-week double-blind dose-finding study was performed in which subjects ingested placebo capsules or test capsules containing 16 mg, 32 mg or 48 mg of isohumulones per day.

Result – After treatment, fasting blood glucose was decreased ……in the (HOPS group) after 4 weeks, but did not change in the placebo group. HbA1c was also significantly decreased after 4 weeks in the … (Hops group) Body mass index (BMI) was significantly decreased in the 48 mg group as compared with the placebo group at 12 weeks. The decrease in total fat area was also significantly greater in the 48 mg group than in the placebo group at 12 weeks.

Cutting Inflammation and Joint Pain

  • Modulates hyaluronan activity in the joints (joint cushion)
  • Reduces collagen degradation
  • Inhibits proteoglycan loss
  • Anti-inflammatory (reduces inflammation)
  • Natural pain reliever
  • Numerous other health benefits

In this study, we demonstrate and compare the anti-inflammatory effect of various classes of hop bitter acids (HBA), including α-acids (AA), β-acids (BA), and iso-α-acids (IAA), in fibroblasts, which are important players in the inflammatory response. All three studied classes of HBA blocked the tumor necrosis factor alpha (TNF)-induced production of the cytokine IL6, and inhibited the transactivation of the pro-inflammatory transcription factors nuclear factor kappa B (NF-κB)

Reduces Stubborn Belly Fat, Produces weight Loss


Two hundred subjects (male and female aged 20 to below 65 years with a BMI of 25 or more and less than 30 kg/m2) were randomly assigned to two groups. …..The primary endpoint was reduction of the abdominal fat area as determined by CT scanning after continual ingestion of MHE for 12 weeks.


Compared to the placebo group, a significant reduction was observed in the visceral fat area after 8 and 12 weeks, and in the total fat area after 12 weeks in the active group. …


The present study suggests that continual ingestion of MHE safely reduces body fat, particularly the abdominal visceral fat of healthy overweight subjects.

Medical Nutrition focusing on Hops Study

Another major review looked at a number of other issues that are helped by hops its main author is Dr Jeffery Bland.

“Jeffrey Bland Internationally recognized as the father of Functional Medicine, an expert on nutrition and biochemistry, and a healthcare thought leader. Dr. Bland is known as the “father of functional medicine,” and over the past thirty-five years has taught more than 100,000 health-care practitioners around the globe. ” – Dr. Oz

It is suggested from this extensive body of work that specific isohumulones may be important bioactive agents for the application in medical nutrition therapy in the support of diseases associated with chronic inflammation and insulin resistance.”

Below is his (and colleagues) review study on Hops

Bland, Jeffery et all, Isohumulones from hops (humulus lupulus) and their potential role in medical nutrition therapy. Pharma Nutrition 3 (2015) 46-52 Click here to view!

They determined that Hops bitters had a lot of potentially positive medical effects. From the studies they found that hops:

  • Cuts inflammation
  • Reduces insulin resistance
  • Reduced elevated triglycerides
  • Raised good cholesterol
  • Reduced liver fat stores
  • Reduced arthritic pain
  • Is an approved food additive
  • Increases nitric oxide production (think Viagra)
  • Cuts pain like asprin or ibuprofen but without gut issues
  • May prevent cardio-vascular issues by cutting inflammation
  • Reduces swelling
  • Reduced kidney injury and reduced blood pressure
  • Improves insulin signaling
  • Inhibits obesity
  • Increases fat burning
  • Improves insulin action
  • Cuts leaky gut
  • Improves weight loss

(many of these are in animal model studies)

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