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Think Clearer. Remember More. Naturally.
Iso-alpha activates your gut-brain axis through the vagus nerve. No stimulants. No crash.

How It Works: The Gut-Brain Connection

  • Step 1: bitter iso-alpha acids act on bitter taste receptors in the gut

    STEP 1: Gut

    The extremely bitter-tasting iso-alpha acids in Iso-Alpha act on the Bitter Taste Receptors in the gut.

  • Step 2: the gut hormone CCK stimulates the vagus nerve

    STEP 2: Vagus Nerve

    The gut hormone CCK stimulates the vagus nerve - the connection between the gut and the brain.

  • Step 3: the vagus nerve signals the brain to release acetylcholine, norepinephrine and dopamine

    STEP 3: Brain

    The vagus nerve signals the brain to release more acetylcholine, norepinephrine, and dopamine.

Backed by Science: Over 40 studies on the fast-absorbing compounds in Iso-Alpha show improvements in:

Real World Results

  • John Gingas, Iso-Alpha customer

    John Gingas

    "They are my happy pills!"

  • Smiling woman with gray hair and glasses

    Kristi Anderson

    "Ten years ago I had a brain injury. I've had increasing cognitive issues for the last 10 years. I'm on my third bottle of Iso-Alpha, and my cognition is definitely improving! I'm 77 years old, and I am thrilled to be able to think again! I will never stop taking Iso-Alpha!"

  • Smiling woman with curly dark hair

    Amanda I.

    "Since incorporating Iso-Alpha Brain Health into our weekly rhythm, we've seen so many small improvements to our health. One example is being able to remember information without multiple repetitions. Very neat!"

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Three bottles of Iso-Alpha Brain Health with orange softgels

90-day "Brain Boost" Guarantee

When you take Iso-Alpha you will see that your brain starts to function a bit better each day. This is not an instant recovery but over time (90 days is recommended) you will likely see memory, focus and function improve. 

Try Iso-Alpha Risk Free

Special Pricing For First-Time Customers!
Try Iso-Alpha

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What's Inside

Inside each Iso-Alpha bottle you will find a 30-day supply of brain fuel.
Our bioavailable formula swiftly targets receptors upon ingestion, triggering a hormone release that stimulates the Vagus Nerve – a crucial pathway in the body.

Fresh hop cones and orange Iso-Alpha softgels on a wooden table

Iso-Alpha Acids

The primary ingredient in Iso-Alpha is a patented bio-available complex derived from the Hops plant. Each capsule contains Iso Alpha Acids and essential Polyphenol compounds scientifically proven to improve cognitive functions.

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The Iso Alpha Acids in hops aren't limited to the brain - over 40 medical studies cover a number of medical issues including

✔ Memory Processing
✔ Attention Control
✔ Verbal Skills
✔ Mood Enhancement
✔ Mental Endurance
✔ Cognitive Flexibility
✔ Perceptual Learning
✔ Executive Function

Try Iso Alpha Risk Free
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Subscribe & Save

Try it risk free with our "walk on hot coals" guarantee.  If you're not willing to walk on hot coals to keep your bottle, send it back for a full refund within 90 days.

Subscribe Now

Iso-Alpha Opens the Flood Gates to ...

  • Enhanced Cognitive Function


    Activate the vagus nerve signaling the brain to release more acetylcholine, norepinephrine, and dopamine.

    Focus, Learning, Mood & Memory 
  • Improved Memory and Focus


    Boost your brain health by targeting the fdnc5 gene, which increases the production of the Irisin hormone, enhancing mental function and overall well-being.

    Mood, Creativity & Motivation 
  • Enhanced Mood


    Stimulate your gut-brain connection, naturally increasing norepinephrine, a key brain chemical linked to reducing symptoms of depression and ADHD.

    Energy, Focus, Learning & Mood 
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  • Non-GMO
  • GMA
  • ISO 9001
  • Made in the USA
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Special Intro Pricing

This is your best chance to try iso-Alpha!

  • Iso-Alpha Brain Health bottle, front view — hops extract brain supplement, 30 softgels

    Trial Offer: 1 Bottle

    Was: $79.99
    $59.99

    90 Day Guarantee

    Buy Now 
  • Two-month supply: two bottles of Iso-Alpha Brain Health

    Great Value: 2 Bottles

    Was: $140
    $101.98

    90 Day Guarantee + Free Shipping

    Buy Now 
  • Three-month supply: three bottles of Iso-Alpha Brain Health

    Best Value: 3 Bottles

    Was: $179.99
    $130.02

    90 Day Guarantee + Free Shipping

    Buy Now 

Questions You've Been Wondering

Will I feel the immediate effect of Iso-Alpha?

No, you will not feel an immediate effect. However, we guarantee within 90 days you will notice an improvement in your cognitive function, and mood.

What sets Iso Alpha apart from other products?

Most nootropics are botanicals that are destroyed in the stomach. Then, they travel in blood stream as proteins or nutrients, unlikely to actually benefit the brain as broken down components.

Iso-Alpha is made bioavailable, going into the stomach and reaching receptors immediately recognized by the body. From there, they cause a hormone release that affects the Vagus Nerve. This is a major nerve in the body.  It signals to the brain release three important chemicals that may improve your cognitive function.

1. Acetylcholine
2. Norepinephrine
3. Dopamine

When you take Iso-Alpha Brain Health you will see that your brain starts to function a bit better each day. This is not an instant recovery but over time (60 days is recommended) you will likely see memory, focus and function improve. 

How do I take Iso Alpha?

Take one capsule daily, preferably with a meal or water.

What does each bottle contain?

Each bottle holds a 30-day supply of brain fuel.

What are the contents of each pill?

Each Iso Alpha soft gel contains 100 mg of Hops Isohumulone and a patented bio-available polyphenol complex, alongside other ingredients such as polyglycerol esters of fatty acids, bovine gelatin, glycerin, purified water, and patented Hops Isohumulone.

Aren't there hops in beer?

Since iso-alpha acids (IAAs) are extracted from hops - the plant used to make beer - you're probably wondering if you can drink your way to enlightenment.

In order to consume the 100mgs that are in a single capsule of iso-Alpha, you would have to drink several six packs of the bitterest IPA beer.

Before you try to order a big bulk sack of hops cones, you should know that eating hops doesn't work either.

That's why we've patented a new way to extract that IAAs hiding inside hop resin, and put them in a bioavailable capsule you take just once a day.

When should I expect to see benefits?

Unlike most nootropics that provide temporary effects, Iso Alpha offers lasting cognitive enhancements.
Significant improvements can typically be observed within 90 days.

What kind of benefits can I expect from taking Iso Alpha?

Iso Alpha, backed by over 40 scientific studies, enhances focus, mood, learning, motivation, creativity, memory, and more.

Is there a return policy if I'm unsatisfied?

You have a 90-day window to return the product for a refund, even if the bottle has been opened. We stand by our product's efficacy and offer a risk-free trial.