Power up your brain...

without jitters!

Over 40 scientific studies show that the main ingredient in iso-Alpha improves:

Focus

Mood

Learning

Motivation

Creativity

Memory

Slower is Actually Better!

Most nootropics use caffeine to snap your brain to attention... and it quickly wears off. But iso-Alpha permanently upgrades cognitive function - in just 90 days!

Enlightenment...in a Pill?

Since the dawn of human history shamans, monks, artists, and bio-hackers have been infatuated with practices that unlok "enlightened" montal states...

Cold Showers

Deep Breathing

Yoga Postures

What do these practices have in common?

They stimulate the vagus nerve - which signals the brain to release "happy chemicals" that unleash creativity, help you focus, and make you feel good.

Over 80 medical studies show that iso-alpha acids(IAAs) found in the hops plant can stimulate the vagus nerve in a very similar way.

Now you can upgrade your brain in seconds a day... no yoga mat required!

Hacking the Gut/Brain Connection

STEP 1: GUT

Insert the Key

The extremely bitter-tasting iso-alpha acids in iso-Alpha act on the Bitter Taste Receptors in the gut.

STEP 2: VAGUS NERVE

Send The Signal

The gut hormone CCK stimulates the vagus nerve - the connection between the gut and the brain.

STEP 3: BRAIN

Open the Gate

The vagus nerve signals the brain to release more acetylcholine, norepinephrine, and dopamine.

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Opens the Flood Gates to More...

Learning with Acetylcholine

A chill brain is a happy brain - and acetylcholine relaxes your body and brain to prime them for learing.

Focus

Learning

Mood

Memory

Concentration with Norepinephrine

When it's time to mobilize the brain to action, your nervous system needs norepinephrine - deficiencies are linked to depression and ADHD.

Energy

Focus

Learning

Mood

Success with Dopamine

he would (and your brain) runs on dopamine - it's the neurotransmitter that helps your think, strive, plan, and achieve.

Mood

Creativity

Mood

Motivation

One Ingredient

with many health benefits!

The IAAs in hops aren't limited to the brain - over 80 medical studies cover a number of medical issues including...

Energy

Inflammation

Joint Pain

Insulin Resistance

Metabolism

Leaky Gut

Supplement Facts

Serving Size 1 capsule

Serving Per Container 30

Amount per Serving

Hops Isohumulone 100mg

Daily Value not Established

Contains: oleic, linoleic and stearic fatty acids and essential oils.

OTHER INGREDIENTS:

Polyoxyl Castor oil and hydroxypropylmethyl-cellulose(vegetable capsule), patented Hops Isohumulone and favonoid (polyphenol) formula.

EXCLUSIVE PATENTED BIOAVAILABLE HOPS FORMULATION

*If pregnant or nursing or have a serious medical condition consult your doctor before use.

You might be wondering...

"Aren't There Hops in Beer?"

Since iso-alpha acids (IAAs) are extracted from hops - the plant used to make beer - you're probably wondering if you can drink your way to enlightenment.

Well just so you know... In order to consume the 100mgs that are in a single capsule of iso-Alpha, you would have to down several six packs of the bitterest IPA beer.

Now, before you attempt that experiment - let me just tell you that we've already tried, and it definitely did NOT help us get more done at our desk. :-)

And before you try to order a big bulk sack of hops cones, you should know that eating hops doesn't work either.

That's why we've patented a new way to extract that IAAs hiding inside hop resin, and put them in a bioavailable capsule you take just once a day.

Special Pricing For First-Time Customers!

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Upgrade Your Brain ...in Just 90 Days!

Memory Processing

Attention Control

Verbal Skills

Gratification

Mental Endurance

Cognitive Flexibility

Perceptual Learning

Executive Function

Spatial Memory

Special Pricing For First-Time Customers!

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90 Day "Brain Boost"

GUARANTEE

Use iso-Alpha every day for 90 days - and if you don't notice an impressive lift in your cognitive abilities - we'll gladly refund what you paid for our products!

Micah Lowe

Founder and CEO

iso-Alpha

Special Intro Pricing

This is your best chance to try iso-Alpha!

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$90

$79.99

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Medical Studies

  • Livingston, G.;Sommerlad, A.; Orgeta, V.;Costafreda, S.G.; Huntley, J.; Ames, D.; Ballard, C.; Banerjee, S.; Burns, A.; Cohen-Mansfield, J. Dementia prevention, intervention, and care. Lancet 2017, 390, 2673–2734. [CrossRef]
  • Neafsey, E.J.; Collins, M.A. Moderate alcohol consumption and cognitive risk.Neuropsychiatr. Dis. Treat.2011, 7, 465–484. [CrossRef] [PubMed]
  • Xu, W.; Wang, H.; Wan, Y.; Tan, C.; Li, J.; Tan, L.; Yu, J.T. Alcohol consumption and dementia risk: A dose-response meta-analysis of prospective studies. Eur. J. Epidemiol. 2017, 32, 31–42. [CrossRef] [PubMed]
  • Bastianetto, S.; Menard, C.; Quirion, R. Neuroprotective action of resveratrol.Biochim. Biophys. Acta 2015, 1852, 1195–1201. [CrossRef] [PubMed] 
  • Turner, R.S.; Thomas, R.G.; Craft, S.; van Dyck, C.H.; Mintzer, J.; Reynolds, B.A.; Brewer, J.B.; Rissman, R.A.; Raman, R.; Aisen, P.S. A randomized, double-blind, placebo-controlled trial of resveratrol for Alzheimer disease. Neurology 2015, 85, 1383–1391. [CrossRef] 
  • Sawda, C.; Moussa, C.; Turner, R.S. Resveratrol for Alzheimer’s disease.Ann. N. Y. Acad. Sci.2017, 1403, 142–149. [CrossRef] 
  • Biendl, M.;Pinzl, C. Hops and health.MBAA TQ 2009, 46, 1–7. [CrossRef] CrossRef] Biomolecules 2020, 10, 131 11 of 15 
  • Milligan, S.R.; Kalita, J.C.;Heyerick, A.; Rong, H.; De Cooman, L.; DeKeukeleire, D. Identification of a potent phytoestrogen in hops (Humulus lupulus L.) and beer. J. Clin. Endocrinol. Metab. 1999, 84, 2249–2252. 
  • Stulikova, K.; Karabin, M.; Nespor, J.; Dostalek, P. Therapeutic Perspectives of 8-Prenylnaringenin, a Potent Phytoestrogen from Hops. Molecules 2018, 23, 660. [CrossRef] 
  • Liu, M.; Hansen, P.E.; Wang, G.; Qiu, L.; Dong, J.; Yin, H.; Qian, Z.; Yang, M.; Miao, J. Pharmacological profile of xanthohumol, a prenylated flavonoid from hops (Humulus lupulus). Molecules 2015, 20, 754–779. [CrossRef] 
  • Intelmann, D.;Batram, C.; Kuhn, C.; Haseleu, G.; Meyerhof, W.; Hofmann, T. Three TAS2R Bitter Taste Receptors Mediate the Psychophysical Responses to Bitter Compounds of Hops (Humulus lupulus L.) and Beer. Chemosens. Percept. 2009, 2, 118–132. [CrossRef] 
  • Kowaka, M.; Kokubo, E. Composition of bitter substances of hops and characteristics of beer bitterness. Am. Soc. Brew. Chem.1977,35, 16–21. [CrossRef] 
  • Kunimune, T.; Shellhammer, T.H. Foam-stabilizing effects and cling formation patterns of iso-alpha-acids and reduced iso-alpha-acids in lager beer. J. Agric. Food Chem. 2008, 56, 8629–8634. [CrossRef] 
  • Simpson,W.J.; Smith, A.R. Factors affecting antibacterial activity of hop compounds and their derivatives. Appl.Bacteriol.1992, 72, 327–334. [CrossRef] 
  • Schurr, B.C.; Hahne, H.; Kuster, B.; Behr, J.; Vogel, R.F. Molecular mechanisms behind the antimicrobial activity of hop iso-alpha-acids in Lactobacillus brevis. Food Microbiol. 2015, 46, 553–563. [CrossRef] 
  • Taniguchi, Y.;Matsukura, Y.; Taniguchi, H.; Koizumi, H.; Katayama, M. Development of preparative and analytical methods of the hop bitter acid oxide fraction and chemical properties of its components. Biosci. Biotechnol. Biochem. 2015, 79, 1684–1694. [CrossRef]
  • Biessels, G.J.;Staekenborg, S.; Brunner, E.; Brayne, C.; Scheltens, P. Risk of dementia in diabetes mellitus: A systematic review. Lancet Neurol. 2006, 5, 64–74. [CrossRef] 
  • Gudala, K.; Bansal, D.; Schifano, F.; Bhansali, A. Diabetes mellitus and risk of dementia: A meta-analysis of prospective observational studies. J. Diabetes Investig. 2013, 4, 640–650. [CrossRef] 
  • Xu,W.; Atti, A.; Gatz, M.; Pedersen, N.; Johansson, B.;Fratiglioni, L. Midlife overweight and obesity increase late-life dementia risk: A population-based twin study. Neurology 2011, 76, 1568–1574. [CrossRef] 
  • Waldstein, S.; Katzel, L. Interactive relations of central versus total obesity and blood pressure to cognitive function. Int. J. Obes. 2006, 30, 201. [CrossRef] 
  • Raji, C.A.; Ho, A.J.;Parikshak, N.N.; Becker, J.T.; Lopez, O.L.; Kuller, L.H.; Hua, X.; Leow, A.D.; Toga, A.W.; Thompson, P.M. Brain structure and obesity. Hum. Brain Mapp. 2010, 31, 353–364. [CrossRef] 
  • Spencer, S.J.; D’Angelo, H.; Soch, A.; Watkins, L.R.; Maier, S.F.; Barrientos, R.M. High-fat diet and aging interact to produce neuroinflammation and impair hippocampal-and amygdalar-dependent memory. Neurobiol. Aging 2017, 58, 88–101. [CrossRef] 
  • Yajima, H.;Ikeshima, E.; Shiraki, M.; Kanaya, T.; Fujiwara, D.; Odai, H.;Tsuboyama-Kasaoka, N.; Ezaki, O.; Oikawa, S.; Kondo, K. Isohumulones, bitter acids derived from hops, activate both peroxisome proliferator-activated receptor alpha and gamma and reduce insulin resistance. J. Biol. Chem. 2004, 279, 33456–33462. [CrossRef] 
  • Gross, B.; Pawlak, M.; Lefebvre, P.;Staels, B. PPARs in obesity-induced T2DM,dyslipidaemia and NAFLD. Nat. Rev. Endocrinol. 2017, 13, 36–49. [CrossRef]